The recommended starting dose is one 30 mg tablet, taken 1 to 3 hours before you anticipate having sex. Your doctor may later decide to increase your dose to one 60 mg tablet. Your doctor will only prescribe the higher dose for you if the 30 mg dose is insufficient, and providing you have not experienced any side-effects such as feeling faint.Abrupt discontinuation of chronically administered SSRIs used to treat chronic depressive disorders has been reported to result in the following symptoms: dysphoric mood, irritability, agitation, dizziness, sensory disturbances e. In phase 3 studies, Priligy 30 mg was associated with a higher incidence of accidental injuries 2. Precautions to be taken before handling or administering the medicinal product. Following oral dosing in a clinical study designed to explore the metabolism of 14C-dapoxetine, dapoxetine was extensively metabolised to multiple metabolites primarily through the following biotransformational pathways: N-oxidation, N-demethylation, naphthyl hydroxylation, glucuronidation and sulfation. CYP2D6 polymorphism. Adverse drug reactions reported by Priligy treated subjects in these trials are shown in Table 2. A careful appraisal of individual benefit risk of Priligy should be performed by the physician after the first four weeks of treatment or at least after 6 doses of treatment to determine whether continuing treatment with Priligy is appropriate.The most common adverse drug reactions (≥ 5%) reported during clinical trials at a dose of 30 mg Priligy were headache, dizziness and nausea. The most common events leading to discontinuation were nausea (% of 30 mg Priligy treated subjects) and dizziness (% of 30 mg Priligy treated subjects). Priligy 30 mg film−coated tablets are light grey, round, convex, approximately mm in diameter and debossed with “30” inside a triangle on one side. Priligy 60 mg film−coated tablets are grey, round, convex, approximately 8 mm in diameter and debossed with “60” inside a triangle on one side. The recommended starting dose is one 30 mg tablet, taken 1 to 3 hours before you anticipate having sex. Your doctor may later decide to increase your dose to one 60 mg tablet. Your doctor will only prescribe the higher dose for you if the 30 mg dose is insufficient, and providing you have not experienced any side-effects such as feeling faint.Such complications can arise immediately upon delivery. Priligy should be used with caution in patients with raised intraocular pressure or those at risk of angle closure glaucoma. For these reasons, before you start taking dapoxetine it is important that your doctor knows: If you have a tendency to faint. Prodromal symptoms often preceded the syncope see Section 4. Three of the studies were 12 weeks in duration C, C, RPRE , and one study was 24 weeks of treatment followed by a one week assessment of possible withdrawal effects RPRE
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